Publications
Now showing items 1-20 of 680
Social Work
(2023)
This edited volume, Social Work – Perspectives on Leadership and Organisation, presents a variety of perspectives and reflections from social work theories and practice on how to manage, lead and organize social work in ...
Chapter 11 Metabolomics in the Analysis of Inflammatory Diseases
(2012)
Most infections and traumatic injuries are cleared or repaired relatively rapidly and metabolic homoeostasis is soon restored. However, there is a broad range of inflammatory
diseases which involve chronic activation of ...
Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target
(2013)
In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable ...
Chapter 4 Applications of Monte Carlo Simulation in Modelling of Biochemical Processes
(2012)
The biochemical models describing complex and dynamic metabolic systems are typically multi-parametric and non-linear, thus the identification of their parameters requires nonlinear
regression analysis of the experimental ...
Anopheles mosquitoes
(2013)
Anopheles mosquitoes are highly important insects due to their involvement in the transmission of human malaria and its devastating consequences in endemic countries worldwide. In 2010 alone, malaria was responsible for ...
Applications of Monte Carlo Methods in Biology, Medicine and Other Fields of Science
(2011)
This volume is an eclectic mix of applications of Monte Carlo methods in many fields of research should not be surprising, because of the ubiquitous use of these methods in many fields of human endeavor. In an attempt to ...
Senescence
(2012)
The book "Senescence" is aimed to describe all the phenomena related to aging and senescence of all forms of life on Earth, i.e. plants, animals and the human beings. The book contains 36 carefully reviewed chapters written ...
Chapter 31 Central Immune Senescence, Reversal Potentials
(2012)
Ageing is a complex process that affects all living organisms. Senescence is not only conceivable in multicellular organisms, but also in unicellulars. Unlike certain diseases that
have specific morbidity rates, ageing ...
Chapter 5 Computational Analysis and Integration of MeDIP-seq Methylome Data
(2016)
The combinatorial number of possible methylomes in biological time and space is astronomical. Consequently, the computational analysis of methylomes needs to cater for a variety of data, throughput and resolution. Here, ...
Chapter 8 Highlights on Anopheles nili and Anopheles moucheti, Malaria Vectors in Africa
(2013)
In this chapter, we review knowledge gained so far on mosquitoes from An. moucheti and closely related species, as well as the An. nili complex. We highlight specific bionomical, ecological and genetic attributes that ...
Next Generation Sequencing - Advances, Applications and Challenges
(2016)
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction ...
Drug Discovery
(2013)
Natural products are a constant source of potentially active compounds for the treatment of various disorders. The Middle East and tropical regions are believed to have the richest supplies of natural products in the world. ...
Metabolomics
(2012)
Metabolomics is a rapidly emerging field in life sciences, which aims to identify and quantify metabolites in a biological system. Analytical chemistry is combined with sophisticated informatics and statistics tools to ...
Chapter 13 Modelling Seismic Wave Propagation for Geophysical Imaging
(2012)
The Earth is an heterogeneous complex media from the mineral composition scale (10−6m) to the global scale ( 106m). The reconstruction of its structure is a quite challenging problem because sampling methodologies are ...
Chapter 8 Signalling DNA Damage
(2012)
During our lifetime, the genome is constantly being exposed to different types of damage caused either by exogenous sources (radiations and/or genotoxic compound) but also as byproducts of endogenous processes (reactive ...
Chapter 1 Alloy Steel: Properties and Use First-Principles Quantum Mechanical Approach to Stainless Steel Alloys
(2011)
Accurate description of materials requires the most advanced atomic-scale techniques from both experimental and theoretical areas. In spite of the vast number of available techniques,
however, the experimental study of ...
Chapter 3 Optoelectronics and Bio Devices on Paper Powered by Solar Cells
(2017)
The employment of printing techniques as cost-effective methods to fabricate low cost,
flexible, disposable and sustainable solar cells is intimately dependent on the substrate
properties and the adequate electronic ...
Nanostructured Solar Cells
(2017)
Nanostructured solar cells are very important in renewable energy sector as well as in environmental aspects, because it is environment friendly. The nano-grating structures (such as triangular or conical shaped) have a ...
Chapter 3 Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approach for Emerging Blood-Borne Pathogens in Canada
(2012)
In October 2009 it was reported that 68 of 101 patients with chronic fatigue syndrome (CFS) in the United States, when tested, were infected with a novel gamma retrovirus, xenotropic
murine leukemia virus-related virus ...
Chapter 9 Poisson Noise Removal in Spherical Multichannel Images: Application to Fermi Data
(2012)
The Fermi Gamma-ray Space Telescope, which was launched by NASA in June 2008, is a powerful space observatory which studies the high-energy gamma-ray sky Atwood (2009).
Fermi’s main instrument, the Large Area Telescope ...