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        Chapter Genomes

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        Author(s)
        Harb, Omar
        Boehme, Ulrike
        Crouch, Kathryn
        Ifeonu, Olukemi
        Roos, David
        Silva, Joana
        Silva-Franco, Fatima
        Svärd, Staffan
        Tretina, Kyle
        Weedall, Gareth
        Collection
        Wellcome
        Language
        English
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        Abstract
        In the last decade, the rise of affordable affordable high-throughput sequencing technologies has led to rapid advances across the biological sciences. At the time of writing, annotated reference genomes are available within most clades of eukaryotic pathogens, and including un-annotated sequences over 550 genomes are available in total. This This has greatly facilitated studies in many areas of parasitology. In addition, the volume of functional genomics data, including analysis of differential differential transcription and DNA-protein interactions, has increased exponentially. With this unprecedented increase in publicly available data, tools to search and compare datasets are also becoming ever more important. A number of database resources are available, and access to these has become fundamental for a majority of research groups. This This chapter discusses the current state of genomics research for a number of eukaryotic parasites, discussing the genome and functional genomics resources available at the time of writing and highlighting functionally important or unique aspects of the genome for each group. In addition publicly accessible database resources pertaining to eukaryotic parasites are also discussed.
        Book
        Molecular Parasitology
        URI
        https://library.oapen.org/handle/20.500.12657/49611
        Keywords
        biological sciences; genomes; parasitology; genomics research; eukaryotic parasites
        ISBN
        9783709114162, 9783709114155, 9783709148792
        Publisher
        Springer Nature
        Publisher website
        https://www.springernature.com/gp/products/books
        Publication date and place
        2016
        Grantor
        • Wellcome Trust
        Classification
        Medical parasitology
        Pages
        37
        Rights
        https://creativecommons.org/licenses/by/4.0/
        • Imported or submitted locally

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        License

        • If not noted otherwise all contents are available under Attribution 4.0 International (CC BY 4.0)

        Credits

        • logo EU
        • This project received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 683680, 810640, 871069 and 964352.

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