The onset of concomitant global crises generates unexpected phenomena: “great resignation, great upgrade, reshuffle”, by people both with lower levels of education and low salaries, and with higher levels of education and retributions. Our contribution highlights some factors underlying these processes: 1) search for jobs with a greater degree of personal fulfilment. 2) Aspiration for a better balance between work and private life (better “work-life balance”). 3) Desire for a work environment free of "toxic company culture". Consequently, job switching and reshuffling of work activities are cross-sectoral, taking on different forms in the various countries, including Italy. This leads to important challenges for the organizational models of firms and public labour policies.