Publications
Now showing items 1-60 of 680
Social Work
(2023)
This edited volume, Social Work – Perspectives on Leadership and Organisation, presents a variety of perspectives and reflections from social work theories and practice on how to manage, lead and organize social work in ...
Chapter 11 Metabolomics in the Analysis of Inflammatory Diseases
(2012)
Most infections and traumatic injuries are cleared or repaired relatively rapidly and metabolic homoeostasis is soon restored. However, there is a broad range of inflammatory
diseases which involve chronic activation of ...
Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target
(2013)
In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable ...
Chapter 4 Applications of Monte Carlo Simulation in Modelling of Biochemical Processes
(2012)
The biochemical models describing complex and dynamic metabolic systems are typically multi-parametric and non-linear, thus the identification of their parameters requires nonlinear
regression analysis of the experimental ...
Anopheles mosquitoes
(2013)
Anopheles mosquitoes are highly important insects due to their involvement in the transmission of human malaria and its devastating consequences in endemic countries worldwide. In 2010 alone, malaria was responsible for ...
Applications of Monte Carlo Methods in Biology, Medicine and Other Fields of Science
(2011)
This volume is an eclectic mix of applications of Monte Carlo methods in many fields of research should not be surprising, because of the ubiquitous use of these methods in many fields of human endeavor. In an attempt to ...
Senescence
(2012)
The book "Senescence" is aimed to describe all the phenomena related to aging and senescence of all forms of life on Earth, i.e. plants, animals and the human beings. The book contains 36 carefully reviewed chapters written ...
Chapter 31 Central Immune Senescence, Reversal Potentials
(2012)
Ageing is a complex process that affects all living organisms. Senescence is not only conceivable in multicellular organisms, but also in unicellulars. Unlike certain diseases that
have specific morbidity rates, ageing ...
Chapter 5 Computational Analysis and Integration of MeDIP-seq Methylome Data
(2016)
The combinatorial number of possible methylomes in biological time and space is astronomical. Consequently, the computational analysis of methylomes needs to cater for a variety of data, throughput and resolution. Here, ...
Chapter 8 Highlights on Anopheles nili and Anopheles moucheti, Malaria Vectors in Africa
(2013)
In this chapter, we review knowledge gained so far on mosquitoes from An. moucheti and closely related species, as well as the An. nili complex. We highlight specific bionomical, ecological and genetic attributes that ...
Next Generation Sequencing - Advances, Applications and Challenges
(2016)
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction ...
Drug Discovery
(2013)
Natural products are a constant source of potentially active compounds for the treatment of various disorders. The Middle East and tropical regions are believed to have the richest supplies of natural products in the world. ...
Metabolomics
(2012)
Metabolomics is a rapidly emerging field in life sciences, which aims to identify and quantify metabolites in a biological system. Analytical chemistry is combined with sophisticated informatics and statistics tools to ...
Chapter 13 Modelling Seismic Wave Propagation for Geophysical Imaging
(2012)
The Earth is an heterogeneous complex media from the mineral composition scale (10−6m) to the global scale ( 106m). The reconstruction of its structure is a quite challenging problem because sampling methodologies are ...
Chapter 8 Signalling DNA Damage
(2012)
During our lifetime, the genome is constantly being exposed to different types of damage caused either by exogenous sources (radiations and/or genotoxic compound) but also as byproducts of endogenous processes (reactive ...
Chapter 1 Alloy Steel: Properties and Use First-Principles Quantum Mechanical Approach to Stainless Steel Alloys
(2011)
Accurate description of materials requires the most advanced atomic-scale techniques from both experimental and theoretical areas. In spite of the vast number of available techniques,
however, the experimental study of ...
Chapter 3 Optoelectronics and Bio Devices on Paper Powered by Solar Cells
(2017)
The employment of printing techniques as cost-effective methods to fabricate low cost,
flexible, disposable and sustainable solar cells is intimately dependent on the substrate
properties and the adequate electronic ...
Nanostructured Solar Cells
(2017)
Nanostructured solar cells are very important in renewable energy sector as well as in environmental aspects, because it is environment friendly. The nano-grating structures (such as triangular or conical shaped) have a ...
Chapter 3 Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approach for Emerging Blood-Borne Pathogens in Canada
(2012)
In October 2009 it was reported that 68 of 101 patients with chronic fatigue syndrome (CFS) in the United States, when tested, were infected with a novel gamma retrovirus, xenotropic
murine leukemia virus-related virus ...
Chapter 9 Poisson Noise Removal in Spherical Multichannel Images: Application to Fermi Data
(2012)
The Fermi Gamma-ray Space Telescope, which was launched by NASA in June 2008, is a powerful space observatory which studies the high-energy gamma-ray sky Atwood (2009).
Fermi’s main instrument, the Large Area Telescope ...
Chapter 9 Laser Pulses Characterization with Pyroelectric Sensors
(2010)
There are many industrial and medical applications of CO2 (λ=10.6 μm) and Nd:YAG (λ=1.06 μm) infrared lasers for which the quality of the process are tightly connected to the
characteristic of the laser pulse. These two ...
Seismic Waves - Research and Analysis
(2012)
The importance of seismic wave research lies not only in our ability to understand and predict earthquakes and tsunamis, it also reveals information on the Earth's composition and features in much the same way as it led ...
The Continuum of Health Risk Assessments
(2012)
This book presents a collection of health risk assessments for known and emerging hazards that span a continuum. Case studies for existing health risks include psychoactive drug usage in delivery truck drivers and using ...
Progress in Molecular and Environmental Bioengineering - From Analysis and Modeling to Technology Applications
(2011)
This book provides an example of the successful and rapid expansion of bioengineering within the world of the science. It includes a core of studies on bioengineering technology applications so important that their progress ...
Laser Pulse Phenomena and Applications
(2010)
Pulsed lasers are available in the gas, liquid, and the solid state. These lasers are also enormously versatile in their output characteristics yielding emission from very large energy pulses to very high peak-power pulses. ...
Wavelet Transforms and Their Recent Applications in Biology and Geoscience
(2012)
This book reports on recent applications in biology and geoscience. Among them we mention the application of wavelet transforms in the treatment of EEG signals, the dimensionality reduction of the gait recognition framework, ...
Alloy Steel - Properties and Use
(2011)
The sections in this book are devoted to new approaches and usages of stainless steels, the influence of the environments on the behavior of certain classes of steels, new structural concepts to understand some fatigue ...
Protein Phosphorylation in Human Health
(2012)
15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human ...
Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies
(2011)
Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species
(ROS, produced by water radiolysis) ...
Chapter 2 Exploring the Components of the Universe Through Higher-Order Weak Lensing Statistics Higher-Order Weak Lensing Statistics
(2012)
Our current cosmological model, backed by a large body of evidence from a variety of different cosmological probes (for example, see [1, 2]), describes a Universe comprised of
around 5% normal baryonic matter, 22% cold ...
Chapter 15 Brain Tumors and the Lynch Syndrome
(2011)
Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by
germline mutation in one of the DNA mismatch ...
Chapter 4 Numerical Modelling of Industrial Induction
(2011)
Induction heating is a physical process extensively used in the metallurgical industry for different applications involving metal melting. The main components of an induction heating
system are an induction coil connected ...
Chapter 7 Aptamer-Nanoparticle Bioconjugates for Drug Delivery
(2012)
Drug delivery systems traditionally relied on passive diffusion mechanisms for targeting and releasing of therapeutically active molecules. The major problems associated with
traditional delivery are poor specificity ...
Open Questions in Cosmology
(2012)
In the last years we have witnessed how the field of Cosmology has experienced a metamorphosis. From being essentially the search for three numbers (the expansion rate, the deceleration parameter, and the cosmological ...
The Delivery of Nanoparticles
(2012)
Nanoparticle is a general challenge for today's technology and the near future observations of science. Nanoparticles cover mostly all types of sciences and manufacturing technologies. The properties of this particle are ...
Advances in Cancer Therapy
(2011)
The book "Advances in Cancer Therapy" is a new addition to the Intech collection of books and aims at providing scientists and clinicians with a comprehensive overview of the state of current knowledge and latest research ...
Management of CNS Tumors
(2011)
Management of CNS Tumors is a selected review of Central Nervous System (CNS) tumors with particular emphasis on pathological classification and complex treatment algorithms for each common tumor type. Additional detailed ...
Chapter 8 Computational Modelling of the Steps Involved in Photodynamic Therapy
(2012)
Photodynamic therapy (PDT) is a branch of phototherapy that has seen a surge of interest in the last few decades, due to its potential in the treatment of various cancers, infections and
heart disease.(Bonnett, 2000) ...
Chapter 10 Pathogen and Toxin Entry - How Pathogens and Toxins Induce and Harness Endocytotic Mechanisms
(2012)
Humans have been exposed to a plethora of pathogens (bacteria, viruses) ever since. Infectious diseases are among the leading causes of death worldwide. For example, in 2011, 1.34 million people died of tuberculosis, which ...
Chapter 3 Wavelet Analysis for the Extraction of Morphological Features for Orthopaedic Bearing Surfaces
(2011)
Surface texture is one of the most critical factors and important functionality indicators in the performance of high precision and nanoscale devices and components. The functions
that have been identified in various ...
Chapter 11 Crystal Growth and Stoichiometry of Strongly Correlated Intermetallic Cerium Compounds
(2012)
Strongly correlated electron systems are among the most active research topics in modern condensed matter physics. In strongly correlated materials the electron interaction energies
dominate the electron kinetic energy ...
Chapter 14 Laser Plasma Accelerators: Towards High Quality Electron Beam
(2010)
In 1979 Tajima and Dawson, Tajima & Dawson (1979), on the basis of theoretical work and simulations, have shown that relativistic plasma waves are suitable for the development of
compact accelerators. In the proposed ...
Chapter 11 Photoacoustics — A Novel Tool for the Study of Aquatic Photosynthesis
(2013)
The photoacoustic method allows direct determination of the energy-storage efficiency of photosynthesis by relating the energy stored by it to the total light energy absorbed by the plant material (Canaani et al., 1988; ...
Molecular Photochemistry - Various Aspects
(2012)
There have been various comprehensive and stand-alone text books on the introduction to Molecular Photochemistry which provide crystal clear concepts on fundamental issues. This book entitled "Molecular Photochemistry - ...
Modern Aspects of Bulk Crystal and Thin Film Preparation
(2012)
In modern research and development, materials manufacturing crystal growth is known as a way to solve a wide range of technological tasks in the fabrication of materials with preset properties. This book allows a reader ...
Molecular Regulation of Endocytosis
(2012)
Molecular Regulation of Endocytosis is a compilation of scientific "short stories" about the entry of external substances into cells. As one can see from the chapters, endocytosis regulates diverse processes such as ...
Photosynthesis
(2013)
Among the myriads of volumes dedicated to various aspects of photosynthesis, the current one is singular in integrating an update of the most recent insights on this most important biological process in the biosphere. While ...
Chapter 11 Charge Carrier Dynamics in Organometal Halide Perovskite Probed by Time-Resolved Electrical Measurements
(2016)
This chapter presents the fate of the charge carriers from the moment of its photogeneration in the perovskite to injection and transport into electrodes. Time-resolved electrical measurement techniques, terahertz (THz) ...
Chapter 8 Non-thermal Plasma Technology for the Improvement of Scaffolds for Tissue Engineering and Regenerative Medicine - A Review
(2016)
Non-thermal plasma technology is one of those techniques that suffer relatively little from diffusion limits, slow kinetics, and complex geometries compared to more traditional liquid-based chemical surface modification ...
Chapter 5 Plasma Modified Textiles for Biomedical Applications
(2015)
In the textile market industry, technical textiles are one of the fastest growing businesses. Part of that industry consists of textiles for medical and healthcare applications and are responsible for a continuous increase ...
Plasma Science and Technology - Progress in Physical States and Chemical Reactions
(2016)
In the early twentieth century, Dr. Irving Langmuir actively studied plasma discharge and surface science. Since then, great progress has been made in the development of applications of discharges and plasmas such as ...
Perovskite Materials - Synthesis, Characterisation, Properties, and Applications
(2016)
The book summarizes the current state of the know-how in the field of perovskite materials: synthesis, characterization, properties, and applications. Most chapters include a review on the actual knowledge and cutting-edge ...
Advances in Induction and Microwave Heating of Mineral and Organic Materials
(2011)
The book offers comprehensive coverage of the broad range of scientific knowledge in the fields of advances in induction and microwave heating of mineral and organic materials. Beginning with industry application in many ...
Advances in Bioengineering
(2015)
The technological approach and the high level of innovation make bioengineering extremely dynamic and this forces researchers to continuous updating. It involves the publication of the results of the latest scientific ...
Modelling and Control of Switched Reluctance Machines
(2020)
Today, switched reluctance machines (SRMs) play an increasingly important role in various sectors due to advantages such as robustness, simplicity of construction, low cost, insensitivity to high temperatures, and high ...
Artificial Intelligence in Oncology Drug Discovery and Development
(2020)
There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is ...
Carbon-Based Material for Environmental Protection and Remediation
(2020)
Carbon-Based Material for Environmental Protection and Remediation presents an overview of carbon-based technologies and processes, and examines their usefulness and efficiency for environmental preservation and remediation. ...
Advances in Neural Signal Processing
(2020)
Neural signal processing is a specialized area of signal processing aimed at extracting information or decoding intent from neural signals recorded from the central or peripheral nervous system. This has significant ...
Lithium-ion Batteries
(2020)
The book “Lithium-ion Batteries - Thin Film for Energy Materials and Devices” provides recent research and trends for thin film materials relevant to energy utilization. The book has seven chapters with high quality content ...
A Diffusion Hydrodynamic Model
(2020)
The Diffusion Hydrodynamic Model (DHM), as presented in the 1987 USGS publication, was one of the first computational fluid dynamics computational programs based on the groundwater program MODFLOW, which evolved into the ...